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What we know and what we don't know about the perioperative use of methadone in children and adolescents

Pediatric Anesthesia

Reviewed July 2023 by Dr Sorcha Evans

Summary This review article looks at methadone use in the paediatric perioperative population summarising the benefits and risks. A brief description of the pharmacokinetics and pharmacodynamics...

Population Pharmacokinetics of Single Bolus Dose Fentanyl in Obese Children

Anesthesia Analgesia

Reviewed June 2024 by Dr Mark Moll

Background: Childhood obesity is a significant problem. Obesity may alter the pharmacokinetics (PKs) of many medications. Fentanyl is commonly used in paediatric anaesthesia, but there is a...

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