Comparison of the efficacy of intranasal atomised dexmedetomidine versus intranasal atomised ketamine as a premedication for sedation and anxiolysis in children undergoing spinal dysraphism surgery
A randomized controlled trial.
European Journal of Anaesthesiology
Reviewed July 2024 by Dr Ben Blaise
This is a prospective randomised double blind trial in a single paediatric tertiary centre. 64 children aged 1 to 10y referred for elective spinal dysraphism surgery. Patients were randomly...
Effect of BIS-guided anesthesia on emergence delirium following general anesthesia in children
A prospective randomized controlled trial
Anaesthesia Critical Care & Pain Medicine
Reviewed February 2024 by Dr Priya Sreedharan
This prospective, randomised, double-blinded study was conducted at the University hospital of Ostrava in the Czech Republic. The study hypothesized that optimizing the depth of general anaesthesia...
The effect of intranasal dexmedetomidine administration on emergence agitation or delirium in pediatric patients after general anesthesia
A meta-analysis of randomized controlled trials
Pediatric Anesthesia
Reviewed September 2023 by Dr Matt Jenke
Summary: This article is a meta-analysis of randomised control trials analysing the effect of preoperative intranasal dexmedetomidine on emergence agitation (EA) and emergence delirium (ED) in...
Comparison of intravenous and inhalation anesthesia on postoperative behavior changes in children undergoing ambulatory endoscopic procedures
A randomized clinical trial
Pediatric Anesthesia
Reviewed March 2023 by Dr Priya Sreedharan
This randomized, parallel, double-blinded clinical trial performed in an outpatient endoscopic clinic between October 2018 and December 2021 was designed to determine if intravenous anaesthesia was...
Respiratory Adverse Events After LMA® Mask Removal in Children
A Randomized Trial Comparing Propofol to Sevoflurane
Anesthesia Analgesia
Reviewed January 2023 by Dr Justin Skowno
This RCT in 134 low risk children having general anaesthesia with an LMA were randomized between propofol and sevoflurane anaesthesia, with fentanyl analgesia, awake LMA removal and other clinical...
