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Dr Andrew Hughes

Browse reviews written by this Journal Watch contributor.
The Children's Hospital at Westmead
Effects of Dexmedetomidine-Remifentanil on Neurodevelopment of Children after Inhalation Anesthesia

A Randomized Clinical Trial.

Anesthesiology

Submitted January 2026 by Dr Andrew Hughes

This prospective, double-blind RCT compares the neurodevelopmental effect of a single GA exposure using different doses of sevoflurane in children under 2 years of age. Children were randomised to...

Tags: #neurodevelopment· #pharmacology· #non-opioid-analgesics· #opioids· #volatile-anaesthetics

International multiinstitutional external validation of preoperative risk scores for 30 day in hospital mortality in paediatric patients

British Journal of Anaesthesia

Submitted March 2025 by Dr Andrew Hughes

This is an external validation study of two patient-specific paediatric preoperative risk scores for 30-day in-hospital mortality The Pediatric Risk Assessment (PRAm) score and the intrinsic...

Tags: #perioperative· #neonatal

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