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Population Pharmacokinetics of Single Bolus Dose Fentanyl in Obese Children
Anesthesia Analgesia
Background: Childhood obesity is a significant problem. Obesity may alter the pharmacokinetics (PKs) of many medications. Fentanyl is commonly used in paediatric anaesthesia, but there is a paucity...
What we know and what we don't know about the perioperative use of methadone in children and adolescents
Pediatric Anesthesia
Summary This review article looks at methadone use in the paediatric perioperative population summarising the benefits and risks. A brief description of the pharmacokinetics and pharmacodynamics is...
