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Prolonged opioid use after surgery in children, adolescents, and young adults

A systematic review

Canadian Journal of Anaesthesia

July 2025 by Dr Maximiliane Beck

Persistent use of opioids after surgery remains a significant concern in the paediatric population and has been the subject of debate, particularly in North America. In Australia, between 2013 and...

Population Pharmacokinetics of Single Bolus Dose Fentanyl in Obese Children

Anesthesia Analgesia

June 2024 by Dr Mark Moll

Background: Childhood obesity is a significant problem. Obesity may alter the pharmacokinetics (PKs) of many medications. Fentanyl is commonly used in paediatric anaesthesia, but there is a paucity...

Prevalence and Outcomes of Opioid Use Disorder in Pediatric Surgical Patients

A Retrospective Cohort Study.

Anesthesia Analgesia

January 2023 by Dr David Sainsbury

This was a retrospective matched cohort study examining the prevalence of opioid use disorder (OUD) in 10 to 18-year-olds and the association with post-operative outcomes over a 15-year period from...

Health Care Burden Associated With Adolescent Prolonged Opioid Use After Surgery

Anesthesia Analgesia

January 2023 by Dr David Sainsbury

Summary This was a retrospective cohort study of opioid-naïve patients aged 12-21 undergoing surgery. The study used insurance claim data to examine the healthcare usage of the patients and the...

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