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A Randomized Controlled Trial of Intrathecal versus Caudal Morphine-Bupivacaine on Postoperative Analgesia and Cortisol Levels in Pediatric Patients
Bupivacaine on Postoperative Analgesia and Cortisol Levels in Pediatric Patients
Anesthesia Analgesia
September 2025 by Dr Stephanie Pauling
This study compared the analgesic outcomes of caudal morphine and bupivacaine with intrathecal morphine and bupivacaine in patients aged 1-5 having general, urological and orthopaedic surgery below...
Comment on "Safety of Intrathecal Clonidine as an Adjuvant to Spinal Anesthesia in Infants and Children".
Pediatric Anesthesia
September 2025 by Dr David Roche
This retrospective chart review explores the safety of intrathecal clonidine in infants and children up to 3 years of age who received spinal anaesthesia. In this single centre study the authors...
Impact of liberal preoperative clear fluid fasting regimens on the risk of pulmonary aspiration in children (EUROFAST)
An international prospective cohort study
British Journal of Anaesthesia
September 2025 by Dr Meghan Cooney
The EUROFAST (European Preoperative Fasting Audit) project demonstrated that more liberal clear fluid fasting (≥1 hour) before anaesthesia in children is non-inferior to the more traditional ≥2 hour...
Is the Compassion of Anesthesiologists Associated With Postoperative Pain and Patient Experience? A Prospective Cohort Study
Anesthesia Analgesia
September 2025 by Dr Andrew O’Donoghue
This study, published in Anaesthesia & Analgesia (2025), investigates the role of anaesthesiologist compassion in shaping postoperative outcomes among patients undergoing same-day surgery. The...
The promise of precision
Exploring the role of remimazolam in paediatric anaesthesia
British Journal of Anaesthesia
This narrative review serves as an update on the use of remimazolam in paediatric population. The introduction of remimazolam is a notable development in hypnotics in the past two...
Evaluation of the Pediatric Regional Anesthesia Time-Out Checklist
A Simulation Study
Pediatric Anesthesia
This simulation-based study examined the effect of a Paediatric Regional Anaesthesia Time-out Checklist training for pediatric anaesthetists and trainees. Not surprisingly it found that checklist...
Safety and Sustainability of Axillary Versus Radial Arterial Catheters in Critically Ill Children
A Retrospective Comparative Study
Pediatric Anesthesia
August 2025 by Dr Eamonn Upperton
This retrospective cohort study examines axillary arterial lines placed in PICU patients to compare their safety profile with radial arterial lines, and provides some baseline data to support their...
Regional Analgesia in Pediatric Cardiothoracic Surgery
A Bayesian Network Meta-analysis
Journal of Cardiothoracic and Vascular Anaesthesia
July 2025 by Dr Aisling Gormley
This meta-analysis compared the effect of 13 different epidural and regional anaesthetic techniques (ERATs) on opioid consumption and pain scores in paediatric patients following cardiothoracic...
Electroencephalography and Anesthetic Depth in Children Under 2 Years of Age
A Prospective Observational Study
Pediatric Anesthesia
This single-centre prospective observational study aimed to compare EEG spectral parameters during periods of false positive elevations in processed EEG indices to elevations in these indices during...
The Influence of Electroencephalographic Density Spectral Array Guidance of Sevoflurane Administration on Recovery From General Anesthesia in Children. A Randomized Controlled Trial
Pediatric Anesthesia
Single centre, prospective randomised controlled trial conducted at Sophia Children’s Hospital, a tertiary paediatric hospital in Rotterdam, Netherlands, between September 2022 and March 2024 ...
Racial Disparities in Pediatric Anesthesia
An Updated Review
Anesthesiology Clinics
July 2025 by Dr Megan Wellbeloved
This narrative review serves as an update of a previous paper published in 2020 by the same authors. It serves to highlight continued racial disparities in the provision of perioperative care in...
Dorsal penile nerve block versus caudal block for circumcision in pediatric patients
A systematic review and meta-analysis
Trends in Anaesthesia and Critical Care
A systematic review and meta-analysis comparing dorsal penile nerve block (DPNB) versus caudal block (CB), in addition to general anaesthesia, for paediatric patients undergoing circumcision. Primary...
Retrospective Cohort Study of Perioperative Complications in Symptomatic and Asymptomatic Children Testing SARS-CoV-2-Positive Within 21 Days Before Surgery
CoV-2-Positive Within 21 Days Before Surgery
Pediatric Anesthesia
July 2025 by Dr Liam O'Doherty
This is a single centre, retrospective cohort study of 523 paediatric patients who tested positive to COVID 19 within 21 days prior to surgery. Data was acquired via chart review. The primary outcome...
Prolonged opioid use after surgery in children, adolescents, and young adults
A systematic review
Canadian Journal of Anaesthesia
July 2025 by Dr Maximiliane Beck
Persistent use of opioids after surgery remains a significant concern in the paediatric population and has been the subject of debate, particularly in North America. In Australia, between 2013 and...
Caudal Block, High Flow Oxygen Insufflation and Dexmedetomidine Sedation for Infant Inguinal Hernia Surgery-An Analysis of Post-Study Implementation Into Clinical Practice.
An Analysis of Post-Study Implementation Into Clinical Practice.
Pediatric Anesthesia
This study is a prospective, multicentre, observational study across two Australian centres and one New Zealand centre. The aim was to assess the feasibility of intravenous dexmedetomidine, high-flow...
Design considerations for development of cuffed endotracheal tube for small airways
Pediatric Anesthesia
This paper and the work relating to the design of endotracheal tubes specifically for the paediatric population was sponsored and funded by Medtronic. The article begins by introducing technical...
Awake Supraglottic Airway Placement in Pediatric Patients for Airway Obstruction or Difficult Intubation
Insights From an International Airway Registry (PeDI)
Anesthesia Analgesia
A large, prospective, observational study using data from the international, multi-centre PEDI registry. Data was contributed from 18 institutions. All cases of awake supraglottic airway (SGA)...
International multiinstitutional external validation of preoperative risk scores for 30 day in hospital mortality in paediatric patients
British Journal of Anaesthesia
March 2025 by Dr Andrew Hughes
This is an external validation study of two patient-specific paediatric preoperative risk scores for 30-day in-hospital mortality The Pediatric Risk Assessment (PRAm) score and the intrinsic...
Consensus on decommissioning piped nitrous oxide from UK and Ireland operating theatre suites
A rational approach to an increasingly ignoble gas
Anaesthesia
This editorial summarises the context and evidence for the release of the July 2024 Consensus statement of the Association of Anaesthetists, Royal College of Anaesthetists, College of...
Analgesic efficacy and safety of erector spinae plane block in pediatric patients undergoing elective surgery
A systematic review and Meta-analysis of randomized controlled trials
Journal of Clinical Anesthesia
This systematic review and meta-analysis compared analgesic efficacy and safety between erector spinae plane block (ESPB) and controls in paediatric surgical patients. The primary outcome analysed...
Optimizing pediatric tonsillectomy outcomes with an opioid sparing anesthesia protocol
Learning and continuously improving with real-world data
Pediatric Anesthesia
March 2025 by Dr David Kinchington
This paper is a perspective piece primarily providing insight into how one ambulatory surgical centre utilised quality improvement processes supported by new generation artificial intelligence (AI)...
Short-term Outcomes in Infants after General Anesthesia with Low-dose Sevoflurane/Dexmedetomidine/Remifentanil versus Standard-dose Sevoflurane
The TREX Trial
Anesthesiology
March 2025 by Dr Roeland Passier
This is a secondary analysis comparing the two treatment groups in The Trial Remifentanil DEXmedetomidine (TREX) trial looking at early perioperative results. TREX, which is ongoing, was designed to...
Long-term outcomes of early exposure to repeated general anaesthesia in children with cystic fibrosis (CF-GAIN)
A multicentre, open-label, randomised controlled phase 4 trial
The Lancet
February 2025 by Dr Nicole Wylie
The initial trial was a prospective, open-label, unblinded, randomised and multi-centre trial designed to look at the entirely different clinical question of pulmonary and nutritional outcomes. This...
